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Drug


Eldepryl
selegiline
 



Generic Name:selegiline
Pronounced:seh LEDGE ah leen
Brand Name:Eldepryl

What is the most important information I should know about selegiline?

Do not take larger doses than are prescribed for you. Larger doses will not have any greater effect, but serious side effects could result.
Use caution when driving, operating machinery, or performing other hazardous activities. Selegiline may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

What is selegiline?
Selegiline is used to treat Parkinson's disease. Parkinson's disease is associated with low levels of a chemical called dopamine (doe PA meen) in your brain. The exact way that selegiline works is unknown. However, it is believed that selegiline prevents the breakdown of dopamine in your brain. Selegiline is usually added to a treatment regimen after levodopa/carbidopa therapy begins to deteriorate.
Selegiline is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It is also used to treat the same muscular conditions when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Selegiline may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking selegiline?
Selegiline should not be taken if you are taking meperidine (Demerol).
Before taking selegiline, tell your doctor if you have any other medical conditions. You may require special monitoring or a special dosage because of other conditions or other medicines that you are taking.
Selegiline is in the FDA pregnancy category C. This means that it is not known whether selegiline will harm an unborn baby. Do not take selegiline without first talking to your doctor if you are pregnant.
It is also not known whether selegiline will harm a nursing infant. Do not take selegiline without first talking to your doctor if you are breast-feeding a baby.

How should I take selegiline?

Take selegiline exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Selegiline is usually taken twice a day, at breakfast and lunch. Follow your doctor's directions.
Do not take larger doses than are prescribed for you. Larger doses will not have any greater effect, but serious side effects could result.
Store selegiline at room temperature away from moisture and heat.

What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?
Seek emergency medical attention.
Symptoms of a selegiline overdose include excitement, irritability, nervousness, insomnia, dizziness, severe headache, hallucinations, weakness, sweating, and seizures.

What should I avoid while taking selegiline?
Use caution when driving, operating machinery, or performing other hazardous activities. Selegiline may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Do not take doses higher than those prescribed for you. Higher doses will not have any greater effect, but serious side effects could result.

What are the possible side effects of selegiline?

If you experience any of the following serious side effects, stop taking selegiline and seek emergency medical attention:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • a severe headache;
  • restlessness, agitation, or irritability;
  • sweating;
  • convulsions; or
  • uncontrollable or irregular movements.
Other, less serious side effects may also occur. Continue to take selegiline and talk to your doctor if you experience
  • dizziness or drowsiness;
  • nausea, abdominal pain, or diarrhea;
  • insomnia or vivid dreams;
  • mild confusion, agitation, or anxiety;
  • a mild headache; or
  • dry mouth.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect selegiline?
Before taking selegiline, tell your doctor if you are taking:
  • fluoxetine (Prozac), or
  • meperidine (Demerol).
You may not be able to take selegiline, or you may require a dose adjustment or special monitoring if you are taking either of the medicines listed above.
Drugs other than those listed here may also interact with selegiline. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?
Your pharmacist has more information about selegiline written for health professionals that you may read.

What does my medication look like?
Selegiline is available with a prescription under the brand name Eldepryl. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
  • Eldepryl 5 mg--aqua-blue capsules

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


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