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Drug


tizanidine
generic
 



Generic Name:tizanidine
Pronounced:tye ZA ni dine
Brand Name:Zanaflex

What is the most important information I should know about tizanidine?

Use caution when driving, operating machinery, or performing other hazardous activities. Tizanidine may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities.
Dizziness is most likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
Use caution with alcohol, other muscle relaxants, sleep or anxiety medicines, and pain medicines. These drugs may increase drowsiness and dizziness while you are taking tizanidine. Do not take any other medicine during treatment with tizanidine without first talking to your doctor or pharmacist.

What is tizanidine?
Tizanidine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
Tizanidine is used to treat increased muscle tone associated with spasticity.
Tizanidine may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking tizanidine?
Before taking this medication, tell your doctor if you
  • have liver disease,
  • have kidney disease,
  • have low blood pressure or are on medication to treat high blood pressure; or
  • are taking birth control pills.
You may not be able to take tizanidine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
Tizanidine is in the FDA pregnancy C. This means that it is not known whether tizanidine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
It is not known whether tizanidine passes into breast milk. Do not take tizanidine without first talking to your doctor if you are breast-feeding a baby.

How should I take tizanidine?

Take tizanidine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Tizanidine is usually taken several times a day. Follow your doctor's instructions.
Do not take more than three doses of tizanidine--or more than 36 mg--in 24 hours. Too much of this medication can damage your liver.
Store tizanidine at room temperature away from moisture and heat.

What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?
Seek emergency medical attention.
Symptoms of a tizanidine overdose are not well known but include unconsciousness and irregular breathing.

What should I avoid while taking tizanidine?
Use caution when driving, operating machinery, or performing other hazardous activities. Tizanidine may cause drowsiness and dizziness. If you experience drowsiness or dizziness, avoid these activities.
Dizziness is most likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
Use caution with alcohol, other muscle relaxants, sleep or anxiety medicines, and pain medicines. These drugs may increase drowsiness and dizziness while you are taking tizanidine. Do not take any other medicine during treatment with tizanidine without first talking to your doctor or pharmacist.

What are the possible side effects of tizanidine?

If you experience any of the following serious side effects, stop taking tizanidine and seek emergency medical attention:
  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • hallucinations or abnormal behavior; or
  • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
Other, less serious side effects may be more likely to occur. Continue to take tizanidine and talk to your doctor if you experience
  • drowsiness or dizziness;
  • weakness;
  • dry mouth;
  • increased muscle tone or spasms; or
  • sweating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect tizanidine?
Tizanidine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.
Birth control pills can increase the effects of tizanidine. Tell your doctor if you are taking birth control pills before starting treatment with tizanidine.
Tizanidine may lower blood pressure. Tell your doctor if you are taking another medicine to lower blood pressure or a medicine to treat another heart condition.
Drugs other than those listed here may also interact with tizanidine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?
Your pharmacist has additional information about tizanidine written for health professionals that you may read.

What does my medication look like?
Tizanidine is available with a prescription under the brand name Zanaflex. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
  • Zanaflex 4 mg--white, round tablets

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


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